Defending champion Marin Cilic, former winner Grigor Dimitrov and 2018 Wimbledon finalist Kevin Anderson all lost at the Queen’s Club grass-court tournament on Thursday.
Cilic and Anderson were knocked out in the second round, while Dimitrov didn’t make it past the first round having waited four days to play his opening match.
Diego Schwartzman of Argentina beat the fifth-seeded Cilic 6-4, 6-4 and Anderson, the second seed, was defeated 6-1, 4-6, 6-4 by Gilles Simon.
Dimitrov followed Anderson on Court 1 and fell 6-4, 6-4 to Felix Auger-Aliassime.
Top-seeded Stefanos Tsitsipas ensured he would play two matches in one day at the rain-hit event by beating Kyle Edmund 6-3, 7-5.
Tsitsipas faces Jeremy Chardy later Thursday, while Andy Murray makes his return after a six-month absence because of injury in a doubles match partnering Feliciano Lopez.
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