British Airways owner IAG says the strikes called by pilots in a dispute over pay and conditions have cost it at least €137m (£120m).
As a result of the two-day strike by pilots on 9 and 10 September, IAG said a total of 2,325 flights had been cancelled.
There have been no further talks between BA and Balpa, and more strike action will hit profit, IAG said.
In addition, IAG took a €33m hit over threatened strikes at Heathrow Airport.
Overall, IAG expects its operating profit for this year to be €215m lower than in 2018.